A Southampton cancer charity boss has called for the Government to intervene to stop the shortage of a life-saving drug. 

Neil Pearce from PLANETS Cancer Charity has written to Health Secretary Wes Street outlining his "deep concerns" amid a lack of pancreatic enzyme replacement therapy (Pert).

The former pancreatic cancer surgeon and chairman of the charity - based at University Hospital Southampton - warned that unless action is taken, the shortage could lead to excess deaths.

The treatment is often referred to as Creon, which is the brand name of a commonly-used type of the drug, and is prescribed for patients with pancreatic deficiencies caused by a variety of conditions including pancreatic cancer, pancreatic surgery, cystic fibrosis, chronic pancreatitis and neuroendocrine tumours.

PLANETS, which helps patients with pancreatic, liver, colorectal, abdominal (oesophageal and gastric) and neuroendocrine (NET) cancers, estimates around 20,000 people in the UK are affected by the problem.

Mr Pearce said: “We are deeply concerned that the patients we represent remain at significant risk of avoidable, life-threatening complications due to the shortage of Pert despite a National Patient Safety Agency (NPSA) safety alert being released.

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“I am distressed by the stories I am hearing on a daily basis, including those of palliative pancreatic cancer patients suffering avoidable pain and indignity, and some of my own patients from 20 years ago who are now unable to leave the house because of the severity of their symptoms.

“It is evident that the good intentions of the safety alert and the advice issued alongside it are not making a difference to patients in the community whose lives are now dominated by the search for this essential treatment.”

The NPSA safety alert advises that procurement rules are being relaxed to allow the importation of Pert from unlicensed sources, but Mr Pearce said there is no evidence that patients in the community are getting access to these supplies.

He added: "Every day we hear stories of patients scouring the country for pharmacists with a supply in stock and travelling as much as 100 miles to get a month’s supply or, in some cases, just enough capsules of this medication to last the weekend.”

A lack of adequate Pert leads to malnutrition, with rapid weight loss, fatigue, vitamin and mineral deficiency, susceptibility to infections and, as many of these patients are diabetic, their blood sugars become increasingly difficult to control.

A spokesperson for the charity said the shortage has been caused by a number of factors including supply chain issues across Europe exacerbated by leaving the European Union, the lack of a UK manufacturer, and a worldwide increase in demand due to a rise in the number of patients living with the conditions related to it.

“In addition, current NHS prescribing rules prevent pharmacists from substituting a like-for-like product when a specific brand is specified on the prescription and NHS procurement rules exclude viable supplies from ‘unlicensed’ sources such as US manufacturers", they added. 

The Department for Health and Social Care has been approached for comment.