It's one of the biggest events in the sporting calendar - the Six Nations.

England, Wales, Scotland, Ireland, France and Italy go head-to-head as the tournament returns for the first week of fixtures.

The tournament got underway at 2.15pm with Wales taking on Ireland.

This afternoon, Scotland and England face off at Murrayfield to compete for the Calcutta Cup.

Scotland come into the game with high hopes, off the back of historic wins against England and France last year.

And England will be hoping to improve on their disappointing fifth-place finish in last season's Six Nations.

Daily Echo: Scotland fans gearing up for today's Six Nations clash against England. Picture: PAScotland fans gearing up for today's Six Nations clash against England. Picture: PA

Six Nations Championship: England V Scotland line-up

Sale's Tom Curry captains England for the first time in the absence of Owen Farrell and Courtney Lawes.

The wings have a new look, with Harlequins' Joe Marchant and Saracens' Max Malins, while Elliot Daly and Henry Slade form a new partnership in the centres.

But all eyes will be on Harlequins’ fly-half Marcus Smith, who wears the number 10 shirt.

England team

15. Freddie Steward, 14. Max Malins, 13. Elliot Daly, 12. Henry Slade, 11. Joe Marchant, 10. Marcus Smith, 9. Ben Youngs; 1. Ellis Genge, 2. Luke Cowan-Dickie, 3. Kyle Sinckler, 4. Maro Itoje, 5. Nick Isiekwe, 6. Lewis Ludlam, 7. Tom Curry, 8. Sam Simmonds

Replacements: 16. Jamie George, 17. Joe Marler, 18. Will Stuart, 19. Charlie Ewels, 20. Alex Dombrandt, 21. Harry Randall, 22. George Ford, 23. Jack Nowell

Scotland team

15. Stuart Hogg (Captain), 14. Darcy Graham, 13. Chris Harris, 12. Sam Johnson, 11. Duhan van der Merwe, 10. Finn Russell (Vice-Captain), 9. Ali Price; 1. Rory Sutherland, 2. George Turner, 3. Zander Fagerson, 4. Jonny Gray, 5. Grant Gilchrist, 6. Jamie Ritchie (Vice-Captain), 7. Hamish Watson, 8. Matt Fagerson

Replacements: 16. Stuart McInally, 17. Pierre Schoeman, 18. WP Nel, 19. Sam Skinner, 20. Magnus Bradbury, 21. Ben White, 22 Blair Kinghorn, 23 Sione Tuipulotu

How to watch Scotland v England Six Nations

The Scotland v England Six Nations clash will be shown live on BBC One, BBC iPlayer and online.

It will also air on BBC Radio 5 live and BBC Radio Scotland, with text commentary also available on the BBC Sport website and app.

Kick off is at 4.45pm.